Product Name: TPP1 (D4E2R) Rabbit mAb#14667
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 9007-28-7
Product: Chondroitin (sulfate)
Specificity Sensitivity: TPP1 (D4E2R) Rabbit mAb recognizes endogenous levels of total TPP1 protein.
Species Reactivity: Human, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Glu169 of human TPP1 protein.
Background: TPP1 is encoded by the the ACD gene, and is one of six core proteins of the shelterin complex (TRF1, TRF2, Rap1, TIN2, POT1 and TPP1) that regulates telomere length and integrity. This nuclear protein complex localizes to telomeres, and protects the natur
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/28384194?dopt=Abstract
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