Product Name: SignalStain® Akt Pathway IHC Sampler Kit#8107
Application:
Western Blotting:
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage:
CAS NO.: 81686-22-8
Product: Sodium ionophore III
Specificity Sensitivity: Each antibody in the SignalStain® Akt Pathway IHC Sampler Kit detects endogenous levels of its target protein and does not cross-react with related proteins.
Species Reactivity:
Source Purification: Monoclonal antibody is produced by immunizing animals with synthetic phosphopeptides corresponding to residues surrounding the phosphorylation site(s) of interest, and synthetic peptides corresponding to the carboxy-terminal sequence of mouse Akt or from
Background: The protein kinase Akt (also called PKB or Rac) is activated by insulin and growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase (1,2). Akt is activated by phospholipid binding and activation loop phosphorylation
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18158282?dopt=Abstract
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