Product Name: Phospho-VEGF Receptor 2 (Tyr951) Antibody#2471
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 293753-05-6
Product: SR3335
Specificity Sensitivity: Phospho-VEGF Receptor 2 (Tyr951) Antibody detects endogenous VEGFR-2 only when phosphorylated at Tyr951.
Species Reactivity: Human, Mouse
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr951 of human VEGFR-2. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Vascular endothelial growth factor receptor 2 (VEGFR2, KDR, Flk-1) is a major receptor for VEGF-induced signaling in endothelial cells. Upon ligand binding, VEGFR2 undergoes autophosphorylation and becomes activated (1). Major autophosphorylation sites of
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22154765?dopt=Abstract
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