Product Name: Phospho-Tyrosine (P-Tyr-1000) MultiMab™ Rabbit mAb mix#8954
Application: Dilutions
Western Blotting: 1:2000
Immunoprecipitation: 1:200
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 126860-83-1
Product: MC 1046
Specificity Sensitivity: Phospho-Tyrosine (P-Tyr-1000) MultiMab™ Rabbit mAb mix recognizes a broad range of tyrosine-phosphorylated proteins and peptides. This antibody does not cross-react with proteins or peptides containing phospho-Ser or phospho-Thr residues.
Species Reactivity: All Species Expected
Source Purification: MultiMab™ rabbit monoclonal mix antibodies are prepared by combining individual rabbit monoclonal clones in optimized ratios for the approved applications. Each antibody in the mix is carefully selected based on motif recognition and performance in multip
Background: Tyrosine phosphorylation plays a key role in cellular signaling (1). Research studies have shown that in cancer, unregulated tyrosine kinase activity can drive malignancy and tumor formation by generating inappropriate proliferation and survival signals (
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16528007?dopt=Abstract
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