Product Name: Phospho-Tyrosine Mouse mAb (P-Tyr-102)#9416
Application: Dilutions
Western Blotting: 1:2000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA: 1:1000
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 112827-99-3
Product: 24R-Calcipotriol
Specificity Sensitivity: Phospho-Tyrosine Mouse mAb (P-Tyr-102) is a high affinity IgG1 monoclonal antibody. ELISAs using a wide variety of phospho-peptides show that P-Tyr-102 binds phospho-Tyr in a manner largely independent of the surrounding amino acid sequence.
Species Reactivity: Human, Mouse, Rat, All Species Expected
Source Purification: Monoclonal antibody is produced by immunizing animals with synthetic phospho-Tyr-containing peptides.
Background: Tyrosine phosphorylation plays a key role in cellular signaling (1). Research studies have shown that in cancer, unregulated tyrosine kinase activity can drive malignancy and tumor formation by generating inappropriate proliferation and survival signals (
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17804674?dopt=Abstract
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