Product Name: Phospho-Tyrosine Mouse mAb (P-Tyr-100)#9411
Application: Dilutions
Western Blotting: 1:2000
Immunoprecipitation: 1:100
Immunohistochemistry: 1:4800
Peptide ELISA: 1:4000
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 112875-61-3
Product: Impurity F of Calcipotriol
Specificity Sensitivity: Phospho-Tyrosine Mouse mAb (P-Tyr-100) is a high affinity antibody. ELISAs against a wide variety of phosphopeptides indicate that P-Tyr-100 binds phospho-Tyr in a manner largely independent of the surrounding amino acid sequence. 2D gel Western blot anal
Species Reactivity: Human, Mouse, Rat, All Species Expected
Source Purification: Monoclonal antibody is produced by immunizing animals with phospho-tyrosine containing peptides .
Background: Tyrosine phosphorylation plays a key role in cellular signaling (1). Research studies have shown that in cancer, unregulated tyrosine kinase activity can drive malignancy and tumor formation by generating inappropriate proliferation and survival signals (
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16787646?dopt=Abstract
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