Product Name: Phospho-Tyk2 (Tyr1054/1055) (D7T8A) Rabbit mAb#68790
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1361644-26-9
Product: INNO-206
Specificity Sensitivity: Phospho-Tyk2 (Tyr1054/1055) (D7T8A) Rabbit mAb recognizes endogenous levels of Tyk2 protein only when phosphorylated at Tyr1054 and Tyr1055. Cross-reactivity was not observed with other Jak family members.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phospho-peptide corresponding to residues surrounding Tyr1054/1055 of human Tyk2 protein.
Background: Tyk2 is a member of the Jak family of protein tyrosine kinases. It associates with and is activated by receptors for many cytokines including IL-13, the IL-6 family, IL-10, and IFN-α and β (1-3). Following ligand binding, Tyk2 is activated by phosphorylat
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20699413?dopt=Abstract
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