Product Name: Phospho-Tyk2 (Tyr1054/1055) Antibody#9321
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 67-97-0
Product: Cholecalciferol
Specificity Sensitivity: Phospho-Tyk2 (Tyr1054/1055) Antibody detects endogenous levels of Tyk2 protein only when phosphorylated at Tyr1054/1055. The antibody does not cross-react with Tyk2 protein phosphorylated at other sites.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1054/1055 of human Tyk2 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Tyk2 is a member of the Jak family of protein tyrosine kinases. It associates with and is activated by receptors for many cytokines including IL-13, the IL-6 family, IL-10, and IFN-α and β (1-3). Following ligand binding, Tyk2 is activated by phosphorylat
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19092814?dopt=Abstract
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