Product Name: Phospho-Tuberin/TSC2 (Tyr1571) Antibody#3614
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 104632-27-1
Product: Dexpramipexole (dihydrochloride)
Specificity Sensitivity: Phospho-Tuberin/TSC2 (Tyr1571) Antibody detects endogenous levels of tuberin only when phosphorylated at tyrosine 1571. This antibody does not detect tuberin phosphorylated at other sites.
Species Reactivity: Mouse, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1571 of human tuberin. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Tuberin is a product of the TSC2 tumor suppressor gene and an important regulator of cell proliferation and tumor development (1). Mutations in either TSC2 or the related TSC1 (hamartin) gene cause tuberous sclerosis complex (TSC), an autosomal dominant d
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24867209?dopt=Abstract
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