Product Name: Phospho-Tuberin/TSC2 (Ser1387) (D2R3A) Rabbit mAb#23402
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 63675-72-9
Product: Nisoldipine
Specificity Sensitivity: Phospho-Tuberin/TSC2 (Ser1387) (D2R3A) Rabbit mAb detects endogenous levels of tuberin protein only when phosphorylated at Ser1387. This antibody may also cross-reacts with an unidentified 140 kD protein.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser1387 of human tuberin protein.
Background: Tuberin is a product of the TSC2 tumor suppressor gene and an important regulator of cell proliferation and tumor development (1). Mutations in either TSC2 or the related TSC1 (hamartin) gene cause tuberous sclerosis complex (TSC), an autosomal dominant d
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22140510?dopt=Abstract
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