Product Name: Phospho-IRS-1 (Ser302) (34C7) Rabbit mAb#2491
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1345847-93-9
Product: Altiratinib
Specificity Sensitivity: Phospho-IRS-1 (Ser302) (37C7) Rabbit mAb detects endogenous levels of IRS-1 only when phosphorylated at Ser302.
Species Reactivity: Human, Mouse
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser302 of mouse IRS-1 (equivalent to Ser307 of human IRS-1).
Background: Insulin receptor substrate 1 (IRS-1) is one of the major substrates of the insulin receptor kinase (1). IRS-1 contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain containing proteins that mediate the metabolic and g
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22167471?dopt=Abstract
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