Product Name: Phospho-Bim (Ser77) (D4H12) Rabbit mAb#12433
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 851546-61-7
Product: PSI-697
Specificity Sensitivity: Phospho-Bim (Ser77) (D4H12) Rabbit mAb recognizes endogenous levels of Bim protein only when phosphorylated at Ser77.
Species Reactivity: Human, Mouse
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser77 of human Bim protein.
Background: Bim/Bod is a pro-apoptotic protein belonging to the BH3-only group of Bcl-2 family members including Bad, Bid, Bik, Hrk, and Noxa that contain a BH3 domain but lack other conserved BH1 or BH2 domains (1,2). Bim induces apoptosis by binding to and antagoni
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26338103?dopt=Abstract
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