Product Name: Phospho-Bim (Ser69) Antibody#4581
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 409345-29-5
Product: JNJ16259685
Specificity Sensitivity: Phospho-Bim (Ser69) Antibody detects endogenous levels of Bim protein only when phosphorylated at Ser69.
Species Reactivity: Human, Mouse
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser69 of human Bim protein (Ser65 in mouse and rat). Antibodies are purified by peptide affinity chromatography.
Background: Bim/Bod is a pro-apoptotic protein belonging to the BH3-only group of Bcl-2 family members including Bad, Bid, Bik, Hrk, and Noxa that contain a BH3 domain but lack other conserved BH1 or BH2 domains (1,2). Bim induces apoptosis by binding to and antagoni
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27662663?dopt=Abstract
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