Product Name: Phospho-Bad Antibody Sampler Kit#9105
Application:
Western Blotting:
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage:
CAS NO.: 110448-33-4
Product: ML-7 (hydrochloride)
Specificity Sensitivity: Bad (D24A9) Rabbit mAb detects endogenous levels of total Bad protein. Phospho-Bad (Ser112) (40A9) Rabbit mAb detects endogenous levels of Bad only when phosphorylated at Ser112 (equivalent to Ser75 in human and Ser113 in rat). Phospho-Bad (Ser136) (D25H8
Species Reactivity:
Source Purification: Bad (D24A9) Rabbit mAb (#9239) was prepared by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro102 of human Bad protein. Phospho-specific antibodies (#4366, #5284, #9297) were prepared by respectively immunizing animal
Background: Bad is a proapoptotic member of the Bcl-2 family that promotes cell death by displacing Bax from binding to Bcl-2 and Bcl-xL (1,2). Survival factors, such as IL-3, inhibit the apoptotic activity of Bad by activating intracellular signaling pathways that r
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24901319?dopt=Abstract
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