Product Name: Phospho-BACH1/BRIP1 (Thr1133) Antibody#11983
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 259869-55-1
Product: JWH-133
Specificity Sensitivity: Phospho-BACH1/BRIP1 (Thr1133) Antibody recognizes endogenous levels of BACH1/BRIP1 protein only when phosphorylated at Thr1133. This antibody also cross-reacts with a protein of unknown origin at ~130 kDa.
Species Reactivity: Human, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr1133 of human BACH1/BRIP1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: BACH1, also known as BRIP1 and FANCJ, is a DNA helicase involved in repair of DNA cross-links and double strand breaks (1-3). Interaction between phosphorylated BACH1 and BRCA1 is required for DNA damage-induced checkpoint signaling (3,4). Originally iden
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22535521?dopt=Abstract
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