Product Name: Phospho-ARHGAP42 (Tyr376) (D45E9) Rabbit mAb#5617
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1638750-96-5
Product: ML RR-S2 CDA (ammonium salt)
Specificity Sensitivity: Phospho-ARHGAP42 (Tyr376) (D45E9) Rabbit mAb detects endogenous levels of ARHGAP42 only when phosphorylated at Tyr376.
Species Reactivity: Human, Mouse, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr376 of human ARHGAP42 protein.
Background: ARHGAP family members activate Rho GTPase proteins (1). Mutations of ARHGAP family genes lead to carcinogenesis through the dysregulation of Rho/Rac/Cdc42-like GTPases (2). Little is known about the biological function of ARHGAP42, a member of the ARHGAP
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24465772?dopt=Abstract
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