Product Name: Phospho-AMPKα1 (Ser485) Antibody#4184
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 289480-64-4
Product: Treprostinil (sodium)
Specificity Sensitivity: Phospho-AMPKα1 (Ser485) Antibody detects endogenous levels of AMPKα1 only when phosphorylated at serine 485. The antibody does not cross-react with phosphorylated AMPKα2 or other related proteins.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser485 of human AMPKα1. Antibodies are purified by protein A and peptide affinity chromatography.
Background: AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis (1). AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits,
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22496344?dopt=Abstract
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