Product Name: PD-L1 (E1L3N®) XP® Rabbit mAb#13684
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry: 1:200
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 127917-66-2
Product: Ro 41-1049 (hydrochloride)
Specificity Sensitivity: PD-L1 (E1L3N®) XP® Rabbit mAb recognizes endogenous levels of total PD-L1 protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human PD-L1 protein.
Background: Programmed cell death 1 ligand 1 (PD-L1, B7-H1, CD274) is a member of the B7 family of cell surface ligands that regulate T cell activation and immune responses. The PD-L1 ligand binds the PD-1 transmembrane receptor and inhibits T cell activation. PD-L1
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16496378?dopt=Abstract
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