Product Name: Jak Isoform Sampler Kit#9945
Application:
Western Blotting:
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage:
CAS NO.: 1201438-56-3
Product: Duvelisib
Specificity Sensitivity: Each Jak isoform antibody recognizes endogenous levels of the specified Jak isoform independent of its phosphorylation state. Neither antibody cross-reacts with the two other isoforms.
Species Reactivity:
Source Purification: Each isoform-specific antibody is produced by immunizing animals with a synthetic peptide that is specific for the Jak isoform. Jak1 and Jak3 antibodies are purified by protein A and peptide affinity chromatography. Each Jak antibody included in this kit
Background: Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3, and Tyk2) are activated by ligands binding to a number of associated cytokine receptors (1). Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate the
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24694948?dopt=Abstract
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