Product Name: Cleaved Caspase-1 (Asp296) Antibody#67314
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 300817-68-9
Product: BH3I-1
Specificity Sensitivity: Cleaved Caspase-1 (Asp296) Antibody recognizes endogenous levels of Caspase-1 protein only when cleaved at Asp296.
Species Reactivity: Mouse
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp296 of mouse Caspase-1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Caspase-1, or interleukin-1ß converting enzyme (ICE/ICEα), is a class I cysteine protease, which also includes caspases -4, -5, -11, and -12. Caspase-1 cleaves inflammatory cytokines such as pro-IL-1ß and interferon-γ inducing factor (IL-18) into their ma
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27449062?dopt=Abstract
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