Product Name: Claspin Antibody#2800
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1269055-85-7
Product: MUT056399
Specificity Sensitivity: Claspin Antibody detects endogenous levels of total claspin protein.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to amino acids near the carboxy terminus of human claspin. Antibodies are purified by peptide affinity chromatography.
Background: Originally identified in Xenopus (1), and later in human cells (2), claspin is a mediator of Chk1 signal transduction at the replication checkpoint and in response to DNA damage. Expression of claspin is cell cycle-regulated, with protein levels peaking a
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25015036?dopt=Abstract
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