Product Name: Caspase-8 Antibody (Mouse Specific)#4927
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 36098-33-6
Product: F16
Specificity Sensitivity: Caspase-8 Antibody (Mouse Specific) detects endogenous levels of mouse caspase-8 protein.
Species Reactivity: Mouse
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to a region within the large 18 kDa subunit of mouse caspase-8. Antibodies were purified by protein A and peptide affinity chromatography.
Background: Apoptosis induced through the CD95 receptor (Fas/APO-1) and tumor necrosis factor receptor 1 (TNFR1) activates caspase-8 and leads to the release of the caspase-8 active fragments, p18 and p10 (1-3). Activated caspase-8 cleaves and activates downstream ef
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24591638?dopt=Abstract
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