Product Name: Caspase-1 (D7F10) Rabbit mAb#3866
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1220699-06-8
Product: PF-04979064
Specificity Sensitivity: Caspase-1 (D7F10) Rabbit mAb detects endogenous levels of full length human Caspase-1. The activated p20 subunit was detected by over-expression.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues within the p20 subunit of human caspase-1.
Background: Caspase-1, or interleukin-1ß converting enzyme (ICE/ICEα), is a class I cysteine protease, which also includes caspases -4, -5, -11, and -12. Caspase-1 cleaves inflammatory cytokines such as pro-IL-1ß and interferon-γ inducing factor (IL-18) into their ma
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26111147?dopt=Abstract
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