Product Name: Bax (D3R2M) Rabbit mAb (Rodent Preferred)#14796
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry: 1:400
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 83930-13-6
Product: Human growth hormone-releasing factor
Specificity Sensitivity: Bax (D3R2M) Rabbit mAb (Rodent Preferred) recognizes endogenous levels of total Bax protein in rodent samples. It can detect human Bax protein by western blot, but not by other applications.
Species Reactivity: Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu70 of mouse Bax protein.
Background: Bax is a key component for cellular induced apoptosis through mitochondrial stress (1). Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane (2). Through interactions with pore proteins on the mit
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17483490?dopt=Abstract
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