Product Name: BLM Antibody#2742
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1489389-18-5
Product: CCT245737
Specificity Sensitivity: BLM Antibody detects endogenous levels of total BLM protein.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human BLM. Antibodies are purified by peptide affinity chromatography.
Background: BLM, a member of the RecQ family of DNA helicases, is part of the BRCA1-associated genome surveillance complex (BASC) that responds to DNA damage, stalled replication forks and S phase arrest (1-4). Phosphorylation of BLM helicase at Thr99 and Thr122 occu
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24829906?dopt=Abstract
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