Product Name: Aurora A/AIK Antibody#3092
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1129403-56-0
Product: Amcasertib
Specificity Sensitivity: Aurora A/AIK Antibody detects endogenous levels of total Aurora A/AIK protein. The antibody may cross-react with AIK3.
Species Reactivity: Human, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the amino terminus of human Aurora A/AIK. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Aurora A (AIK) is a cell cycle-regulated Ser/Thr protein kinase that is overexpressed in many tumor cell lines (1-3). Phosphorylation of Aurora A at Thr288 within the kinase activation loop results in a significant increase in its activity and may target
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20061373?dopt=Abstract
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