Product Name: β-Arrestin 1/2 (D24H9) Rabbit mAb#4674
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:200
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1442684-77-6
Product: AM-2394
Specificity Sensitivity: β-Arrestin 1/2 (D24H9) Rabbit mAb detects endogenous level of total beta-arrestin 1 and beta-arrestin 2 proteins.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a recombinant protein containing the carboxy-terminal region of human β-arrestin 1.
Background: Arrestin proteins function as negative regulators of G protein-coupled receptor (GPCR) signaling. Cognate ligand binding stimulates GPCR phosphorylation, which is followed by binding of arrestin to the phosphorylated GPCR and the eventual internalization
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19351736?dopt=Abstract
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