Product Name: Apaf-1 (R205) Antibody#5088
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1429639-50-8
Product: CZ415
Specificity Sensitivity: Apaf-1 (R205) Antibody detects endogenous levels of total Apaf-1 protein.
Species Reactivity: Human, Monkey
Source Purification: Polyclonal antibodies are prepared by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg205 of human Apaf-1 protein. Antibodies were purified by protein A and peptide affinity chromatography.
Background: Apoptotic protease activating factor 1 (Apaf-1), originally identified as the mammalian homolog of the C. elegans apoptotic regulatory protein CED-4, is an important signaling protein involved in the activation of caspase-9 during apoptosis (1). Cytosolic
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20573986?dopt=Abstract
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