Product Name: ATM (11G12) Mouse mAb#92356
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 7083-71-8
Product: Emetine (dihydrochloride hydrate)
Specificity Sensitivity: ATM (11G12) Mouse mAb recognizes endogenous levels of total ATM protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with recombinant protein corresponding to amino acids 992-1144 of human ATM protein.
Background: Ataxia telangiectasia mutated kinase (ATM) is a serine/threonine kinase that regulates cell cycle checkpoints and DNA repair (1). Activation of ATM by autophosphorylation on Ser1981 occurs in response to exposed DNA double stranded breaks. ATM kinase regu
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18464311?dopt=Abstract
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