Product Name: ATF-4 (D4B8) Rabbit mAb#11815
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 37988-18-4
Product: LM22A-4
Specificity Sensitivity: ATF-4 (D4B8) Rabbit mAb recognizes endogenous levels of total ATF-4 protein.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human ATF-4 protein.
Background: ATF-4, an activating transcription factor/cAMP-response element-binding protein family member, functions in the PERK and eIF2α ER stress responsive pathway (1-3). ER stress represses the translation of the majority of mRNAs, but selectively stimulates the
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24132959?dopt=Abstract
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