Product Name: AIM2 (D5X7K) Rabbit mAb#12948
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 141117-12-6
Product: Celgosivir (hydrochloride)
Specificity Sensitivity: AIM2 (D5X7K) Rabbit mAb recognizes endogenous levels of total AIM2 protein. An unknown band is detected at 22 kDa in some cell lines.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Lys93 of human AIM2 protein.
Background: Absent in melanoma 2 (AIM2) is an interferon-inducible protein containing an amino-terminal pyrin domain and carboxy-terminal HIN-200 domain that functions in innate immunity and tumor progression (1). Expression of AIM2 can inhibit cell growth and tumor
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25193543?dopt=Abstract
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