Product Name: 5-Formylcytosine (5-fC) (D5D4K) Rabbit mAb#74178
Application: Dilutions
Western Blotting:
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 2083627-02-3
Product: EED226
Specificity Sensitivity: 5-Formylcytosine (5-fC) (D5D4K) Rabbit mAb detects 5-fC by IF in cells over-expressing the TET1 catalytic domain and by dot blot using double-stranded PCR fragments containing 5-fC. Many cells and tissues contain very low endogenous levels of 5-fC that ma
Species Reactivity: All Species Expected
Source Purification: Monoclonal antibody is produced by immunizing animals with 5-formyl-2-deoxycytosine.
Background: Methylation of DNA at cytosine residues is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting, and mammalian development (1,2). 5-methylcytosine is a repressive epigenetic mark established de
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24686499?dopt=Abstract
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