Product Name: 4E-BP1 (53H11) Rabbit mAb#9644
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry: 1:2400
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 106612-94-6
Product: GLP-1(7-37)
Specificity Sensitivity: 4E-BP1 (53H11) Rabbit mAb detects endogenous levels of total 4E-BP1 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: 4E-BP1 (53H11) Rabbit mAb is produced by immunizing rabbits with a synthetic peptide corresponding to residues surrounding Ser112 of human 4E-BP1.
Background: Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent trans
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27154400?dopt=Abstract
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