Uan ST, Zhao L Common gambogic acids inhibited development of human

Uan ST, Zhao L General gambogic acids inhibited growth of human hepatoma SMMC-7721 cells in vitro and in nude mice. Acta Pharmacol Sin 25: 769774. 17. Qu Bao-Xi HX-G, Li De-Hua The EXperimental Research on Antineoplastic Action of Gambogic II. Chinese Journal of Clinical Oncology 18: 5052. 18. Qu Bao-Xi JY-Z, Zhang Ping, Yu Su-Ping, Li De-Hua The Cytocidal Kinetic Effects of Gamboge II on L1210 Leukemic Cells. Chinese Journal of Clinical Oncology 18: 5356. 19. LIU Jing-bing QS-k, LI Jin, Experimental research of anti-pancreatic cancer with Gambogic Acid. Chinese Clinical Oncology ten. 20. Yang L, Wang M, Cheng H, Li Q . Zhongguo Zhong Yao Za Zhi 36: 12171221. 21. Cheng H, Su JJ, Peng JY, Wang M, Wang XC, et al. AN 3199 Gambogenic acid inhibits proliferation of A549 cells via apoptosis inducing via up-regulation of the p38 MAPK cascade. J Asian Nat Prod Res 13: 9931002. 22. Li Q, Cheng H, Zhu G, Yang L, Zhou A, et al. Gambogenic acid inhibits proliferation of A549 cells by means of apoptosis-inducing and cell cycle arresting. Biol Pharm Bull 33: 415420. 23. Yan F, Wang M, Li J, Cheng H, Su J, et al. Gambogenic acid induced mitochondrial-dependent apoptosis and referred to Phospho-Erk1/2 and Phospho-p38 MAPK in human hepatoma HepG2 cells. Environ Toxicol Pharmacol 33: 181190. 24. Yan F, Wang M, Chen H, Su J, Wang X, et al. Gambogenic acid mediated apoptosis via the mitochondrial oxidative stress and inactivation of Akt signaling pathway in human nasopharyngeal carcinoma CNE-1 cells. Eur J Pharmacol 652: 2332. 25. Yu XJ, Han QB, Wen ZS, Ma L, Gao J, et al. Gambogenic acid induces G1 arrest by way of GSK3beta-dependent cyclin D1 degradation and triggers autophagy in lung cancer cells. Cancer Lett 322: 185194. 26. Li B, Hu Q, Wang H, Man N, Ren H, et al. Omi/HtrA2 can be a good regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases. Cell Death Differ 17: 17731784. 27. Munafo DB, Colombo MI A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation. J Cell Sci 114: 3619 3629. 28. Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402: 672676. 29. Chen S, Rehman SK, Zhang W, Wen A, Yao L, et al. Autophagy is a therapeutic target in anticancer drug resistance. Biochim Biophys Acta 1806: 220229. 30. Turcotte S, Giaccia AJ Targeting cancer cells by way of autophagy for anticancer therapy. Curr Opin Cell Biol 22: 246251. 31. Bareford MD, Park MA, Yacoub A, Hamed HA, Tang Y, et al. Sorafenib enhances pemetrexed cytoHIF-2��-IN-1 biological activity toxicity via an autophagy-dependent mechanism in cancer cells. Cancer Res 71: 49554967. 32. Martin AP, Mitchell C, Rahmani M, Nephew KP, Grant S, et al. Inhibition of MCL-1 enhances lapatinib toxicity and overcomes lapatinib resistance by means of BAK-dependent autophagy. Cancer Biol Ther eight: 20842096. 33. Bhutia SK, Das SK, Azab B, Dash R, Su ZZ, et al. Autophagy switches to apoptosis in prostate cancer cells infected with melanoma differentiation related gene-7/interleukin-24. Autophagy 7: 10761077. 34. Amaravadi RK, Lippincott-Schwartz J, Yin XM, Weiss WA, Takebe N, 1313429 et al. Principles and existing methods for targeting autophagy for cancer remedy. Clin Cancer Res 17: 654666. 35. Kanzawa T, Germano IM, Komata T, Ito H, Kondo Y, et al. Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. Cell Death Differ 11: 448457. 36. Kanematsu S, U.Uan ST, Zhao L Common gambogic acids inhibited growth of human hepatoma SMMC-7721 cells in vitro and in nude mice. Acta Pharmacol Sin 25: 769774. 17. Qu Bao-Xi HX-G, Li De-Hua The EXperimental Research on Antineoplastic Action of Gambogic II. Chinese Journal of Clinical Oncology 18: 5052. 18. Qu Bao-Xi JY-Z, Zhang Ping, Yu Su-Ping, Li De-Hua The Cytocidal Kinetic Effects of Gamboge II on L1210 Leukemic Cells. Chinese Journal of Clinical Oncology 18: 5356. 19. LIU Jing-bing QS-k, LI Jin, Experimental research of anti-pancreatic cancer with Gambogic Acid. Chinese Clinical Oncology 10. 20. Yang L, Wang M, Cheng H, Li Q . Zhongguo Zhong Yao Za Zhi 36: 12171221. 21. Cheng H, Su JJ, Peng JY, Wang M, Wang XC, et al. Gambogenic acid inhibits proliferation of A549 cells by way of apoptosis inducing via up-regulation in the p38 MAPK cascade. J Asian Nat Prod Res 13: 9931002. 22. Li Q, Cheng H, Zhu G, Yang L, Zhou A, et al. Gambogenic acid inhibits proliferation of A549 cells by way of apoptosis-inducing and cell cycle arresting. Biol Pharm Bull 33: 415420. 23. Yan F, Wang M, Li J, Cheng H, Su J, et al. Gambogenic acid induced mitochondrial-dependent apoptosis and referred to Phospho-Erk1/2 and Phospho-p38 MAPK in human hepatoma HepG2 cells. Environ Toxicol Pharmacol 33: 181190. 24. Yan F, Wang M, Chen H, Su J, Wang X, et al. Gambogenic acid mediated apoptosis via the mitochondrial oxidative anxiety and inactivation of Akt signaling pathway in human nasopharyngeal carcinoma CNE-1 cells. Eur J Pharmacol 652: 2332. 25. Yu XJ, Han QB, Wen ZS, Ma L, Gao J, et al. Gambogenic acid induces G1 arrest by means of GSK3beta-dependent cyclin D1 degradation and triggers autophagy in lung cancer cells. Cancer Lett 322: 185194. 26. Li B, Hu Q, Wang H, Man N, Ren H, et al. Omi/HtrA2 is usually a good regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative illnesses. Cell Death Differ 17: 17731784. 27. Munafo DB, Colombo MI A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation. J Cell Sci 114: 3619 3629. 28. Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402: 672676. 29. Chen S, Rehman SK, Zhang W, Wen A, Yao L, et al. Autophagy is actually a therapeutic target in anticancer drug resistance. Biochim Biophys Acta 1806: 220229. 30. Turcotte S, Giaccia AJ Targeting cancer cells through autophagy for anticancer therapy. Curr Opin Cell Biol 22: 246251. 31. Bareford MD, Park MA, Yacoub A, Hamed HA, Tang Y, et al. Sorafenib enhances pemetrexed cytotoxicity by means of an autophagy-dependent mechanism in cancer cells. Cancer Res 71: 49554967. 32. Martin AP, Mitchell C, Rahmani M, Nephew KP, Grant S, et al. Inhibition of MCL-1 enhances lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagy. Cancer Biol Ther 8: 20842096. 33. Bhutia SK, Das SK, Azab B, Dash R, Su ZZ, et al. Autophagy switches to apoptosis in prostate cancer cells infected with melanoma differentiation connected gene-7/interleukin-24. Autophagy 7: 10761077. 34. Amaravadi RK, Lippincott-Schwartz J, Yin XM, Weiss WA, Takebe N, 1313429 et al. Principles and current techniques for targeting autophagy for cancer treatment. Clin Cancer Res 17: 654666. 35. Kanzawa T, Germano IM, Komata T, Ito H, Kondo Y, et al. Function of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. Cell Death Differ 11: 448457. 36. Kanematsu S, U.